"Frequency-Based Brain Networks: From a Multiplex Framework to a Full Multilayer Description"

One of my papers just came out in final form. Here are some details.

Title: Frequency-Based Brain Networks: From a Multiplex Framework to a Full Multilayer Description

Authors: Javier M. Buldú and Mason A. Porter

Abstract: We explore how to study dynamical interactions between brain regions by using functional multilayer networks whose layers represent different frequency bands at which a brain operates. Specifically, we investigate the consequences of considering the brain as (i) a multilayer network, in which all brain regions can interact with each other at different frequency bands; and as (ii) a multiplex network, in which interactions between different frequency bands are allowed only within each brain region and not between them. We study the second-smallest eigenvalue λ2 of the combinatorial supra-Laplacian matrix of both the multiplex and multilayer networks, as λ2 has been used previously as an indicator of network synchronizability and as a biomarker for several brain diseases. We show that the heterogeneity of interlayer edge weights and, especially, the fraction of missing edges crucially modify the value of λ2, and we illustrate our results with both synthetic network models and real data obtained from resting-state magnetoencephalography. Our work highlights the differences between using a multiplex approach and a full multilayer approach when studying frequency-based multilayer brain networks.

Bonus: This paper has an easter egg. Can you find it? (Hint: This is Spinal Tap.)